APJ AS PROMISING THERAPEUTIC TARGET OF PEPTIDE ANALOGUES IN MYOCARDIAL INFARCTION- AND HYPERTENSION-INDUCED HEART FAILURE

APJ as Promising Therapeutic Target of Peptide Analogues in Myocardial Infarction- and Hypertension-Induced Heart Failure

The widely expressed G protein-coupled apelin receptor (APJ) is activated by two bioactive endogenous peptides, apelin and ELABELA (ELA).The apelin/ELA-APJ-related pathway has been found galaxy harmony nc involved in the regulation of many physiological and pathological cardiovascular processes.Increasing studies are deepening the role of the APJ p

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CTTGAN: Traffic Data Synthesizing Scheme Based on Conditional GAN

Most machine learning algorithms only have a good recognition rate on balanced datasets.However, in the field of malicious traffic identification, benign traffic on the network is far greater than malicious traffic, and the network traffic dataset is imbalanced, which makes the algorithm have a low identification rate for small categories of malici

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Relapsed/refractory multiple myeloma-transformed plasma-cell leukemia successfully treated with daratumumab followed by autologous stem cell transplantation

Daratumumab is a humanized anti-CD38 IgG1 monoclonal antibody which could be used for multiple myeloma (MM).MM with plasma-cell leukemia (PCL) transformation is highly aggressive and is resistant to conventional therapy.Novel therapeutics are needed for PCL, and daratumumab may play role.We report a case of relapsed/refractory multiple myeloma (RRM

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